papersSEP 10 04:00 UTC
XAI-Refine: Automated Explanation-Knowledge Loop for Brain-Age Prediction
A new arXiv preprint introduces XAI-Refine, a framework that couples post-hoc explanation methods with a knowledge-refinement loop for brain-age prediction models. The authors argue that high predictive accuracy alone does not show a model relies on reproducible or neurobiologically plausible mechanisms, so explanations are fed back to iteratively improve the model. The approach aims to make brain-age estimates more interpretable and mechanistically grounded.